| Product Name | Melanotan II |
| Chemical Name | Melanotan, Melanotan II, MT, MTII, MT-II, MT2, MT-2, |
| CAS | 121062-08-6 |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | 1024.18 |
| Specification | 10mg/vail |
| Assay | 99.5% |
| Appearance | White powder |
Melanotan may refer to one of two separate peptides : Afamelanotide, originally developed under the names "Melanotan-1" or "Melanotan I" for skin tanning, a drug currently in trials in implant form as a prophylactic treatment for a series of light affected skin disorders and potential skin cancer preventative agent.
Melanotan II (also known as MT-II or MT-2) is an injectable peptide hormone used to promote tanning. MT-II works by stimulating alpha-melanocyte receptors, which promotes formation of melanin in response to sun exposure. When a substantial amount of MT-II has been taken within recent "memory" of the skin cells, an individual tans as if he were a genetically darker type.
Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction
Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.
A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.
Melanotan II requires cumulative dosing to be effective. Depending on the individual, needed cumulative dose will typically be from 10 to 40 mg, with fairer individuals usually requiring amounts at the higher end of the range. Depending on the total amount needed and the daily dosing suitable for the individual, MT-II injections will need to begin at least a week prior to a need for improved tanning. More typically, MT-II use should begin at least a month prior to such need.
Melanotan II can also be used on a cycled basis to maintain improved ability to tan. Further, Melanotan II can be used on occasion for prosexual effect.
For a bodybuilder planning to compete on stage, there is a considerable amount of time and attention to detail committed before they are ready to compete. Being muscled up and defined is only accentuated by a nice tan to make lines and definitions pop out and become more evident to viewers and judges. Enter the heptapeptide Melanotan II, now bodybuilders can actually protect themselves from over exposure to the sun while boosting melanin. This results in a darker and more tanned complexion. When Melanotan II is added to a peptide protocol leading up to a show, it will boost melanin levels, resulting in tanner skin; in addition, it will increase fat loss and muscle hardness.
Melanotan II can also be used on a cycled basis to maintain improved ability to tan.
An example convenient amount of water is 2.5 mL. When this amount of water is used, the resulting solution contains 4 mg of MT-II per mL. If for example wishing to take a dose of 1 mg, a volume of 0.25 mL, or "25 IU" as marked on an insulin syringe, would be taken by injection. Injection may be subcutaneous, intramuscular, or intravenous, according to personal preference.
Injection typically is only once per day, but where a person is first trying the drug and judging tolerance, injection may be divided into two smaller amounts per day.
Typical dosage range is 0.5 to 2.0 mg/day, with a preferred range of 0.5 to 1.0 mg/day. However, it's best to first assess tolerance with lower dosing of 0.25 mg at a time.
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Scientific study on animal test subjects has determined that Meanotan II's ability to produce an uptick in the expression of melanin can conceivably allow it to be a key player in lowering the likelihood of skin cancer development. The main reason behind this thought comes from the peptide's ability to induce the secretion without the harmful effects of ultraviolet rays being part of the process. That said it should be noted that studies indicate that the peptide would not be able to stave off the deadliest form of skin cancer, malignant melanoma, because that particular form of cancer is caused by indirect DNA damage and not exposure to ultraviolet rays.
The effects of Melanotan two revolve around nothing more than tanning and possible erectile dysfunction relief. A darker and deeper tan may be noticed in a few days (assuming one is also tanning) and should produce notable results in a few weeks. The longer one uses MT-2 the darker he will get.
The effects of Melanotan II on erectile dysfunction take approximately 4-6 hours to take effect and should last 6-12 hours depending on individual response. Timing is important if used for this purpose. However, there are those that run small daily to every other day doses in order to provide a maintenance relief, but this can prove problematic to the skin if not careful.
Injection typically is only once per day, but where a person is first trying the drug and judging tolerance, injection may be divided into two smaller amounts per day.
Typical dosage range is 0.5 to 2.0 mg/day, with a preferred range of 0.5 to 1.0 mg/day. However, it's best to first assess tolerance with lower dosing of 0.25 mg at a time.
After reconstitution, a Melanotan II vial should preferably be consumed entirely within 30 days. Prior to reconstitution, MT-II should be stored in the refrigerator or freezer, but it's acceptable for it to be shipped without refrigeration.
Use generally should be discontinued if MT-II, in the individual case, causes problems with increased growth, number, or darkness of moles.
Melanotan II's effect is fairly long-lasting. It can even be the case that it takes a year or more for a cycle's effect to largely disappear. Use of maintenance cycles can maintain effect indefinitely. As a rule of thumb, maintenance typically requires about 2 to 3 times as much MT-II per year as was needed for the first cycle. This can be taken either as a total of 2 to 3 cycles per year done in the same way as the initial cycle, or any more frequent dosing pattern providing this total amount of MT-II per year.
Like every peptide we have discussed thus far, please remember that peptides come in the form of a white delicate powder and should be stored out of light in a cool dry place. All peptides need to be reconstituted with bacteriostatic water or sodium chloride specifically used for injections. In order to use Melanotan II effectively, you need to understand your skin type. To keep things simple, we can go ahead and break skin types into three categories.
Skin Type 1: Very fair skin, never tans. Dosages: 50-60mgs or 5-6vials.
Skin Type 2: Fair skin, burns but sometimes tans. Dosages: 30-40mgs or 3-4 vials.
Skin Type 3: Medium skin, sometimes burns and always tans. Dosages: 20mgs or 2 vials.
Beyond that, if your pigmentation is already naturally olive or darker, you will need to use less Meanotan II for your tanning needs. The tan results coupled with exposure to sunlight and UV rays should last a user all summer or through a season.
| ITEM | SPECIFICATION |
| Appearance | White Crystalline Powder |
| Assay | ≥99% |
| Heavy Metals | ≤10ppm |
| Arsenic | ≤1ppm |
| Lead | ≤3ppm |
| Mercury | ≤0.1ppm |
| Cadmium | ≤1ppm |
| Total Plate Count | ≤1000cfu/g |
| Yeast & Mold | ≤100cfu/g |
| E.Coli | Negative |
| Salmonella | Negative |
| Conclusion | The product conforms to the standard. |
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